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Thyroid function, metabolic parameters and anthropometric changes among Palestinian obese adult females

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dc.contributor.author Mwafy, Saleh
dc.contributor.author Yassin, Maged
dc.contributor.author Mousa, Raed
dc.date.accessioned 2019-11-28T10:47:01Z
dc.date.available 2019-11-28T10:47:01Z
dc.date.issued 2020-03
dc.identifier.uri http://dspace.alazhar.edu.ps/xmlui/handle/123456789/523
dc.description.abstract Objective We sought to evaluate the associations between thyroid hormones, metabolic parameters and anthropometric changes among Palestinian obese adult females. Materials and methods This case-control study included 94 obese and 94 Non-obese female (20–50 years old). Body mass index was determined. Complete blood count, glucose, lipid, protein profile, kidney, liver function, Ca2+, TSH, T3 and T4 levels were evaluated. Results Significant increase in the BMI of obese females compared to control (37.23 ± 4.7 vs. 23.4 ± 1.03, P ≤ 0.001). Hb, HCT MCV, MCH and RDW were decreased significantly in cases compared to control (P ≤ 0.001). The mean levels of TC, TG and LDL-C were significantly increased in cases compared to control (P ≤ 0.01). TSH was significantly decreased (% difference = -32.984 and P ≤ 0.001) while, T3 and T4 were significantly increased among obese compared to non-obese females (% difference = 9.485 and 6.326, P < 0.05, respectively). Statistically significant correlations were reported between different parameters. Conclusions Obesity was correlated with thyroid hormones, metabolic parameters and anthropometric changes among Palestinian obese adult females. The levels of cholesterol, triglyceride, LDL-C, T3 and T4 increase while TSH were decrease with BMI increase. TSH, T3 and T4 are very important tests and frequent monitoring of lipid profile is necessary for obese females. Our findings recommend that obese individuals with relatively higher thyroid hormones, metabolic parameters might benefit more from body weight regulation using a diet intervention strategy for weight loss. en_US
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.relation.ispartofseries Volume 17, March 2020, 100159;1-5
dc.subject Thyroid hormones en_US
dc.subject Anthropometric changes en_US
dc.subject Obesity en_US
dc.subject Gaza en_US
dc.title Thyroid function, metabolic parameters and anthropometric changes among Palestinian obese adult females en_US
dc.type Article en_US


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